SGK1 antibody (N-Term)

Catalog No. ABIN2786820

This Rabbit Polyclonal antibody specifically detects SGK1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig and Horse.

Quick Overview for SGK1 antibody (N-Term) (ABIN2786820)

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SGK1 Antibody

Binding Specificity: N-Term

Sequence: ANPSPPPSPS QQINLGPSSN PHAKPSDFHF LKVIGKGSFG KVLLARHKAE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against SGK1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SGK1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 431 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SGK1

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Alternative Name: SGK1

Background: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell sur
Alias Symbols: SGK
Protein Interaction Partner: AKT1S1, YWHAQ, YWHAZ, MAPT, MTOR, CDKN1B, RPTOR, NEDD4L, Tmem109, Rabac1, GADD45G, UBC, MAGEA1, HSP90AA1, TMEM184C, WNK1, WNK2, WNK4, RAF1, PDPK1, NEDD4, TSC22D3, STUB1, HSPA4, ELAVL1, COMMD1, SYVN1, SCNN1B, RICTOR, PDK1, YPK1, IKBKG, CAMKK1, KCNJ1, GSK3A
Protein Size: 431

Molecular Weight: 49 kDa

Gene ID: 6446

NCBI Accession: NM_005627, NP_005618

UniProt: O00141

Pathways: MAPK Signaling, Notch Signaling, Steroid Hormone Mediated Signaling Pathway