PNOC antibody (Middle Region)

Catalog No. ABIN2786845

This Rabbit Polyclonal antibody specifically detects PNOC in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep and Zebrafish (Danio rerio).

Quick Overview for PNOC antibody (Middle Region) (ABIN2786845)

Target: PNOC (Prepronociceptin (PNOC))

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNOC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PNOC Antibody

Binding Specificity: Middle Region

Purpose: PNOC Antibody - middle region

Sequence: EQEEPEPGME EAGEMEQKQL QKRFGGFTGA RKSARKLANQ KRFSEFMRQY

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PNOC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PNOC

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56692-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PNOC

Target: PNOC (Prepronociceptin (PNOC))

Alternative Name: PNOC

Background:

Background Information: Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. PNOC may be involved in neuronal differentiation and development.

Gene Name: Prepronociceptin

Alternative Symbols: NOP, OFQ, N/OFQ, PPNOC, ppN/OFQ

Protein Name: Prepronociceptin

Molecular Weight: 20kDa

Gene ID: 5368

NCBI Accession: NP_006219

UniProt: Q13519