RAN antibody (Middle Region)

Catalog No. ABIN2786860

The Rabbit Polyclonal anti-RAN antibody is suitable to detect RAN in samples from Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Sheep, Pig, Horse, Rabbit and Saccharomyces cerevisiae. It has been validated for WB.

Quick Overview for RAN antibody (Middle Region) (ABIN2786860)

Target: RAN (RAN, Member RAS Oncogene Family (RAN))

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Sheep, Pig, Horse, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAN Antibody

Binding Specificity: Middle Region

Purpose: RAN Antibody - middle region

Sequence: NLQYYDISAK SNYNFEKPFL WLARKLIGDP NLEFVAMPAL APPEVVMDPA

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RAN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56714-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAN

Target: RAN (RAN, Member RAS Oncogene Family (RAN))

Alternative Name: RAN

Background:

Background Information: RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis an

Gene Name: RAN, member RAS oncogene family

Alternative Symbols: TC4, Gsp1, ARA24

Protein Name: GTP-binding nuclear protein Ran

Molecular Weight: 24kDa

Gene ID: 5901

NCBI Accession: NP_006316

UniProt: P62826

Pathways: Regulatory RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus