RAGE antibody (Middle Region)

Catalog No. ABIN2786878

The Rabbit Polyclonal anti-RAGE antibody has been validated for WB and IHC. It is suitable to detect RAGE in samples from Human, Mouse, Cow, Dog, Guinea Pig, Rabbit, Horse and Goat.

Quick Overview for RAGE antibody (Middle Region) (ABIN2786878)

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Rabbit, Horse, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAGE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RAGE Antibody

Binding Specificity: Middle Region

Sequence: TTNLSPQCLS LLHAMVAYDP DERIAAHQAL QHPYFQEQRK TEKRALGSHR

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%

Characteristics: This is a rabbit polyclonal antibody against RAGE. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAGE

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 419 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAGE

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Alternative Name: RAGE

Background: RAGE is able to phosphorylate several exogenous substrates and to undergo autophosphorylation.
Alias Symbols: MOK, RAGE1, RAGE, RAGE-1
Protein Interaction Partner: UBC, WDR18, SDF4, HUWE1, ZNF223, MOK, INSR, MAPK6, MYC, JUN, CCNB1,
Protein Size: 419

Molecular Weight: 48 kDa

Gene ID: 5891

NCBI Accession: NM_014226, NP_055041

UniProt: Q9UQ07

Pathways: Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins