CRBN antibody (N-Term)

Catalog No. ABIN504115

This Rabbit Polyclonal antibody specifically detects CRBN in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for CRBN antibody (N-Term) (ABIN504115)

Target: CRBN (Cereblon (CRBN))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRBN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRBN Antibody

Binding Specificity: N-Term

Sequence: DQDSKEAKKP NIINFDTSLP TSHTYLGADM EEFHGRTLHD DDSCQVIPVL

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CRBN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CRBN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 442 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRBN

Target: CRBN (Cereblon (CRBN))

Alternative Name: CRBN

Background: This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutatio
Alias Symbols: DKFZp781K0715, MGC27358, MRT2A, MRT2
Protein Interaction Partner: PAK7, RBPMS, MEIS2, DDB1, IKZF3, IKZF1, SUV39H1, KDM1A, UBC, COPS4, COPS6, COPS3, PSMB4, PSMA2, COPS5, CUL4A, PRKAA1, RBX1,
Protein Size: 442

Molecular Weight: 50 kDa

Gene ID: 51185

NCBI Accession: NM_016302, NP_057386

UniProt: Q96SW2