COPS7A antibody (Middle Region)

Catalog No. ABIN2786958

Product Details anti-COPS7A Antibody

Target: COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPS7A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NLKKTIKVTT AAAAAATSQD PEQHLTELRE PAPGTNQRQP SKKASKGKGL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against COPS7A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COPS7A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 275 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COPS7A

Target: COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))

Alternative Name: COPS7A (COPS7A Products)

Synonyms: D6Ertd35e antibody, CSN7A antibody, COP9 signalosome subunit 7A antibody, COPS7A antibody, Cops7a antibody

Background: COPS7A is a component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cul
Alias Symbols: MGC110877, CSN7A
Protein Interaction Partner: FBXW11, RAF1, PTGS2, GPS1, UBC, cul1, COPS6, COPS8, PRMT5, WDR77, COPS7B, DCAF8, EPB41L1, COPS4, FBXO6, FBXW4, VCP, DDIT3, COPS5, COPS2, COPS3, LRR1, DCAF11, DDA1, RFWD2, UBD, RBX1, VPRBP, CUL2, CUL3, CUL4A, CUL4B, GRK5, DDB1, DDB2, DCUN1D1, COPS7A, PMF1,
Protein Size: 275

Molecular Weight: 30 kDa

Gene ID: 50813

NCBI Accession: NM_016319, NP_057403

UniProt: Q9UBW8

Pathways: Cell Division Cycle