PINX1 antibody (N-Term)

Catalog No. ABIN2787040

This Rabbit Polyclonal antibody specifically detects PINX1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Rabbit, Dog and Guinea Pig.

Quick Overview for PINX1 antibody (N-Term) (ABIN2787040)

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PINX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PINX1 Antibody

Binding Specificity: N-Term

Purpose: PINX1 Antibody - N-terminal region

Sequence: EKMGWSKGKG LGAQEQGATD HIKVQVKNNH LGLGATINNE DNWIAHQDDF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PINX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PINX1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57057-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PINX1

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Alternative Name: PINX1

Background:

Background Information: PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. PINX1 mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. PINX1 inhibits telomerase activity and may inhibit cell proliferation and

Gene Name: PIN2/TERF1 interacting, telomerase inhibitor 1

Alternative Symbols: Gno1, LPTL, LPTS, Pxr1

Protein Name: PIN2/TERF1-interacting telomerase inhibitor 1

Molecular Weight: 37kDa

Gene ID: 54984

NCBI Accession: NP_060354

UniProt: Q96BK5