CYP26B1 antibody (N-Term)

Catalog No. ABIN2787182

The Rabbit Polyclonal anti-CYP26B1 antibody is suitable to detect CYP26B1 in samples from Human, Mouse, Rat, Dog, Horse, Rabbit, Cow and Guinea Pig. It has been validated for WB.

Quick Overview for CYP26B1 antibody (N-Term) (ABIN2787182)

Target: CYP26B1 (Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP26B1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CYP26B1 Antibody

Binding Specificity: N-Term

Sequence: LRWAATRDKS CKLPIPKGSM GFPLIGETGH WLLQGSGFQS SRREKYGNVF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CYP26B1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CYP26B1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 512 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CYP26B1

Target: CYP26B1 (Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))

Alternative Name: CYP26B1

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene is involved in the specific inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid.
Alias Symbols: CYP26A2, DKFZp686G0638, MGC129613, P450RAI-2
Protein Interaction Partner: ELAVL1, NEDD4L,
Protein Size: 512

Molecular Weight: 57 kDa

Gene ID: 56603

NCBI Accession: NM_019885, NP_063938

UniProt: Q9NR63

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Monocarboxylic Acid Catabolic Process