BCL7A antibody (Middle Region)

Catalog No. ABIN2787251

This Rabbit Polyclonal antibody specifically detects BCL7A in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for BCL7A antibody (Middle Region) (ABIN2787251)

Target: BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL7A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BCL7A Antibody

Binding Specificity: Middle Region

Purpose: BCL7A Antibody - middle region

Sequence: CGSEVTTPEN SSSPGMMDMH DDNSNQSSIA DASPIKQENS SNSSPAPEPN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against BCL7A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BCL7A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57507-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BCL7A

Target: BCL7A (B-Cell CLL/lymphoma 7A (BCL7A))

Alternative Name: BCL7A

Background:

Background Information: This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: B-cell CLL/lymphoma 7A

Alternative Symbols: BCL7

Protein Name: B-cell CLL/lymphoma 7 protein family member A

Molecular Weight: 25kDa

Gene ID: 605

NCBI Accession: NP_066273

UniProt: Q4VC05