PPM1A antibody (Middle Region)

Catalog No. ABIN2787379

The Rabbit Polyclonal anti-PPM1A antibody (ABIN2787379) specifically detects PPM1A in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig and Horse samples.

Quick Overview for PPM1A antibody (Middle Region) (ABIN2787379)

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPM1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPM1A Antibody

Binding Specificity: Middle Region

Sequence: EIDEHMRVMS EKKHGADRSG STAVGVLISP QHTYFINCGD SRGLLCRNRK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PPM1A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPM1A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 324 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPM1A

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Alternative Name: PPM1A

Background: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the acti
Alias Symbols: MGC9201, PP2C-ALPHA, PP2CA, PP2Calpha
Protein Interaction Partner: DCP1B, HSFY1, UBC, ASB2, RPLP0, HSPB1, NR4A1, FGFR2, SMURF1, SMAD1, ARRB2, ARRB1, SMAD3, DVL2, DVL3, SMAD2, DVL1, GRM3, CACNA1B, CACNA1A, MSN, PRKCD, PIK3R1, AKT1, EEF2, CTNNB1, CACNA1C, LXN,
Protein Size: 324

Molecular Weight: 36 kDa

Gene ID: 5494

NCBI Accession: NM_177951, NP_808820