PPM1B antibody (N-Term)

Catalog No. ABIN2787380

This Rabbit Polyclonal antibody specifically detects PPM1B in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Horse, Cow, Guinea Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for PPM1B antibody (N-Term) (ABIN2787380)

Target: PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))

Reactivity: Human, Rat, Mouse, Dog, Horse, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPM1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPM1B Antibody

Binding Specificity: N-Term

Sequence: EIMEKSGEEG MPDLAHVMRI LSAENIPNLP PGGGLAGKRN VIEAVYSRLN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PPM1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPM1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 192 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPM1B

Target: PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))

Alternative Name: PPM1B

Background: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent
Alias Symbols: MGC21657, PP2C-beta-X, PP2CB, PP2CBETA, PPC2BETAX
Protein Interaction Partner: AURKB, VCP, SUMO2, SUMO3, UBC, SUMO1, GCH1, PAN2, Smurf2, NOS2, ECHS1, MAGOH, YWHAE, EIF4A3, UBL7, FBXO6, ARRB2, ARRB1, VAV2, TLE4, VHL, ISG15, CDK6, IKBKB, MAP3K7, MSN, IKBKG, CDK2, PPP2CA, CHUK, RASGRP1, PABPC4, VIL1, S100A8, KRT18, GSN, ANXA2, ANXA1,
Protein Size: 192

Molecular Weight: 21 kDa

Gene ID: 5495

NCBI Accession: NM_177969, NP_808908

UniProt: Q96ER6