PPM1B antibody

Catalog No. ABIN7246856

Product Details anti-PPM1B Antibody

Target: PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPM1B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human PPM1B

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.72 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPM1B

Target: PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))

Alternative Name: PPM1B (PPM1B Products)

Synonyms: PP2C-beta-X antibody, PP2CB antibody, PP2CBETA antibody, PPC2BETAX antibody, Pp2c2 antibody, fc18g04 antibody, ppm1a antibody, wu:fc18g04 antibody, zgc:92329 antibody, pp2c-beta-x antibody, pp2cb antibody, pp2cbeta antibody, ppc2betax antibody, zgc:92031 antibody, protein phosphatase, Mg2+/Mn2+ dependent 1B antibody, protein phosphatase 1B, magnesium dependent, beta isoform antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1B antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1Bb antibody, protein phosphatase, Mg2+/Mn2+ dependent 1B L homeolog antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1Ba antibody, PPM1B antibody, Ppm1b antibody, ppm1bb antibody, ppm1b.L antibody, ppm1ba antibody

Background: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

UniProt: O75688