RAC1 antibody (Middle Region)

Catalog No. ABIN2787398

The Rabbit Polyclonal anti-RAC1 antibody is suitable to detect RAC1 in samples from Human, Rat, Mouse, Zebrafish (Danio rerio), Dog, Sheep, Rabbit, Horse, Cow and Guinea Pig. It has been validated for WB and IHC.

Quick Overview for RAC1 antibody (Middle Region) (ABIN2787398)

Target: RAC1

Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Dog, Sheep, Rabbit, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RAC1 Antibody

Binding Specificity: Middle Region

Purpose: RAC1 Antibody - middle region

Sequence: LAMAKEIGAV KYLECSALTQ RGLKTVFDEA IRAVLCPPPV KKRKRKCLLL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RAC1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57798-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAC1

Target: RAC1

Background:

Background Information: The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

Alternative Symbols: MIG5, MRD48, Rac-1, TC-25, p21-Rac1

Protein Name: Ras-related C3 botulinum toxin substrate 1

Molecular Weight: 23 kDa

Gene ID: 5879

NCBI Accession: NP_008839

UniProt: P63000

Pathways: WNT Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling