ALDH7A1 antibody (N-Term)

Catalog No. ABIN2787419

This Rabbit Polyclonal antibody specifically detects ALDH7A1 in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Guinea Pig, Zebrafish (Danio rerio), Cow, Horse and Rabbit.

Quick Overview for ALDH7A1 antibody (N-Term) (ABIN2787419)

Target: ALDH7A1 (Aldehyde Dehydrogenase 7 Family, Member A1 (ALDH7A1))

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Zebrafish (Danio rerio), Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH7A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALDH7A1 Antibody

Binding Specificity: N-Term

Purpose: ALDH7A1 Antibody - N-terminal region

Sequence: NQPQYAWLKE LGLREENEGV YNGSWGGRGE VITTYCPANN EPIARVRQAS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ALDH7A1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ALDH7A1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57834-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALDH7A1

Target: ALDH7A1 (Aldehyde Dehydrogenase 7 Family, Member A1 (ALDH7A1))

Alternative Name: ALDH7A1

Background:

Background Information: Antiquitin is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. Mutations in this gene cause pyridoxine-dependent epilepsy, which involves a combination of various seizure types and is responsive to immediate administration of pyridoxine hydrochloride. Four additional human antiquitin-like sequences, all of which are pseudogenes, have also been identified.

Gene Name: Aldehyde dehydrogenase 7 family, member A1

Alternative Symbols: EPD, PDE, ATQ1

Protein Name: Alpha-aminoadipic semialdehyde dehydrogenase

Molecular Weight: 56kDa

Gene ID: 501

NCBI Accession: NP_001173

UniProt: P49419

Pathways: Sensory Perception of Sound