TBX2 antibody (N-Term)

Catalog No. ABIN2787449

The Rabbit Polyclonal anti-TBX2 antibody is suitable to detect TBX2 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for TBX2 antibody (N-Term) (ABIN2787449)

Target: TBX2 (T-Box 2 (TBX2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBX2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TBX2 Antibody

Binding Specificity: N-Term

Purpose: TBX2 Antibody - N-terminal region

Sequence: EAGLHVSALG PHPPAAHLRS LKSLEPEDEV EDDPKVTLEA KELWDQFHKL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 86%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against TBX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TBX2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57903-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TBX2

Target: TBX2 (T-Box 2 (TBX2))

Alternative Name: TBX2

Background:

Background Information: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX2 is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: T-box 2

Alternative Symbols: VETD

Protein Name: T-box transcription factor TBX2

Molecular Weight: 74kDa

Gene ID: 6909

NCBI Accession: NP_005985

UniProt: Q13207

Pathways: p53 Signaling