HNF1A antibody (N-Term)

Catalog No. ABIN2787450

This anti-HNF1A antibody is a Rabbit Polyclonal antibody detecting HNF1A in WB. Suitable for Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Sheep, Zebrafish (Danio rerio) and Rabbit.

Quick Overview for HNF1A antibody (N-Term) (ABIN2787450)

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Sheep, Zebrafish (Danio rerio), Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HNF1A Antibody

Binding Specificity: N-Term

Sequence: HAGQGGLIEE PTGDELPTKK GRRNRFKWGP ASQQILFQAY ERQKNPSKEE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against HNF1A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNF1A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 631 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HNF1A

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Alternative Name: HNF1A

Background: HNF1A is required for the expression of several liver specific genes. HNF1A binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.
Alias Symbols: HNF1, LFB1, MODY3, TCF1, TCF-1, HNF-1A, IDDM20
Protein Interaction Partner: RNF14, RYR3, RAC3, PCBD1, HIST2H2AB, RPSAP15, SNX14, CBX3, YWHAZ, YWHAG, YWHAE, YWHAB, VIM, VCP, HNF1A, SRSF7, RANBP1, PEBP1, LDHA, IGFBP7, HMGB1, ANXA2, ACTB, SIRT1, BCL6, EP300, CREBBP, GATA5, HNF1B, KAT2B, CDX2, HNF4A, TLE1, SRC, FOS, POU2F1, BCR, CEBP
Protein Size: 631

Molecular Weight: 67 kDa

Gene ID: 6927

NCBI Accession: NM_000545, NP_000536

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis