DBP antibody (C-Term)

Catalog No. ABIN2787481

This Rabbit Polyclonal antibody specifically detects DBP in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Horse, Sheep, Guinea Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for DBP antibody (C-Term) (ABIN2787481)

Target: DBP (D Site of Albumin Promoter (Albumin D-Box) Binding Protein (DBP))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Sheep, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DBP Antibody

Binding Specificity: C-Term

Purpose: DBP Antibody - C-terminal region

Sequence: FSEEELKPQP IMKKARKIQV PEEQKDEKYW SRRYKNNEAA KRSRDARRLK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 90%, Rat: 100%, Sheep: 100%, Zebrafish: 80%

Characteristics: This is a rabbit polyclonal antibody against DBP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DBP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57959-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DBP

Target: DBP (D Site of Albumin Promoter (Albumin D-Box) Binding Protein (DBP))

Alternative Name: DBP

Background:

Background Information: DBP is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family. It is transcriptional activator that recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. The protein is not essential for circadian rhythm generation, but modulates important clock output genes.

Gene Name: D site of albumin promoter (albumin D-box) binding protein

Alternative Symbols: DABP, taxREB302

Protein Name: D site-binding protein

Molecular Weight: 34kDa

Gene ID: 1628

NCBI Accession: NP_001343

UniProt: Q10586