Vitronectin antibody (N-Term)

Catalog No. ABIN2787545

This Rabbit Polyclonal antibody specifically detects Vitronectin in WB. It exhibits reactivity toward Human.

Quick Overview for Vitronectin antibody (N-Term) (ABIN2787545)

Target: Vitronectin (VTN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vitronectin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Vitronectin Antibody

Binding Specificity: N-Term

Purpose: VTN Antibody - N-terminal region

Sequence: EDEYTVYDDG EEKNNATVHE QVGGPSLTSD LQAQSKGNPE QTPVLKPEEE

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against VTN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VTN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58095-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Vitronectin

Target: Vitronectin (VTN)

Alternative Name: VTN

Background:

Background Information: VTN is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Vitronectin

Alternative Symbols: VN, V75, VNT

Protein Name: Vitronectin

Molecular Weight: 52kDa

Gene ID: 7448

NCBI Accession: NP_000629

UniProt: P04004

Pathways: Autophagy, Smooth Muscle Cell Migration