Calreticulin antibody (N-Term)

Catalog No. ABIN2787558

The Rabbit Polyclonal anti-Calreticulin antibody (ABIN2787558) specifically detects Calreticulin in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Pig, Dog, Guinea Pig, Cow, Rabbit, Horse and Zebrafish (Danio rerio) samples.

Quick Overview for Calreticulin antibody (N-Term) (ABIN2787558)

Target: Calreticulin (CALR)

Reactivity: Human, Mouse, Rat, Pig, Dog, Guinea Pig, Cow, Rabbit, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calreticulin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Calreticulin Antibody

Binding Specificity: N-Term

Sequence: SSGKFYGDEE KDKGLQTSQD ARFYALSASF EPFSNKGQTL VVQFTVKHEQ

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CALR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CALR

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Calreticulin

Target: Calreticulin (CALR)

Alternative Name: CALR

Background: Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum.
Alias Symbols: CRT, RO, SSA, cC1qR
Protein Interaction Partner: HUWE1, UBC, LGR4, MDM2, RNF2, SUZ12, rev, AARSD1, THG1L, NSUN2, SH3GLB1, EEF2K, ARPC1A, ANP32B, ACTR2, ARPC1B, ARPC3, ARPC5, TPD52L2, SH3GL1, RPA3, RPA1, PRKACA, PFDN5, LPP, PARK2, UPF2, UBD, SOX2, PDIA3, CLN5, ITGA3, HLA-E, HLA-A, CALR, SLC27A2, env, MTN
Protein Size: 417

Molecular Weight: 45 kDa

Gene ID: 811

NCBI Accession: NM_004343, NP_004334

UniProt: P27797

Pathways: Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response