DDAH2 antibody (N-Term)

Catalog No. ABIN2787766

Product Details anti-DDAH2 Antibody

Target: DDAH2 (Dimethylarginine Dimethylaminohydrolase 2 (DDAH2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDAH2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MGTPGEGLGR CSHALIRGVP ESLASGEGAG AGLPALDLAK AQREHGVLGG

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DDAH2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DDAH2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 285 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-DDAH2 antibody (ABIN2787766)

Deer, Krames, Hassenbusch, Burton, Caraway, Dupen, Eisenach, Erdek, Grigsby, Kim, Levy, McDowell, Mekhail, Panchal, Prager, Rauck, Saulino, Sitzman, Staats, Stanton-Hicks, Stearns, Dean Willis, Witt, Follett, Huntoon, Liem, Rathmell, Wallace, Buchser, Cou: "Management of Intrathecal Catheter-Tip Inflammatory Masses: An Updated 2007 Consensus Statement From An Expert Panel." in: Neuromodulation : journal of the International Neuromodulation Society, Vol. 11, Issue 2, pp. 77-91, (2011) (PubMed).

Target Details for DDAH2

Target: DDAH2 (Dimethylarginine Dimethylaminohydrolase 2 (DDAH2))

Alternative Name: DDAH2 (DDAH2 Products)

Synonyms: ddah2 antibody, MGC84290 antibody, g6a antibody, ddah antibody, ng30 antibody, ddahii antibody, MGC89103 antibody, DDAH2 antibody, DDAH antibody, DDAHII antibody, G6a antibody, NG30 antibody, 1110003M04Rik antibody, AU019324 antibody, AW413173 antibody, DDAH-2 antibody, Ddah antibody, dimethylarginine dimethylaminohydrolase 2 antibody, dimethylarginine dimethylaminohydrolase 2 L homeolog antibody, ddah2 antibody, ddah2.L antibody, DDAH2 antibody, Ddah2 antibody

Background: DDAH2 hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. DDAH2 has therefore a role in nitric oxide generation.This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DDAH, DDAHII, G6a, NG30
Protein Interaction Partner: VAC14, UBC, TRIP13, VCAM1, FN1, CDC73, TAF1D, ZAK, DNAJB11, GADD45G, RPS6KA5, TSC22D1, TNFSF11, MKNK1, TK1, STK3, SMN1, RPS6KA1, RAP1B, PIN1, RCC1, CDKN1A, CDK4, ATP1B1, ANXA7,
Protein Size: 285

Molecular Weight: 31 kDa

Gene ID: 23564

NCBI Accession: NM_013974, NP_039268

UniProt: O95865