EPH Receptor A3 antibody (N-Term)

Catalog No. ABIN2787768

This Rabbit Polyclonal antibody specifically detects EPH Receptor A3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse and Rabbit.

Quick Overview for EPH Receptor A3 antibody (N-Term) (ABIN2787768)

Target: EPH Receptor A3 (EPHA3)

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPH Receptor A3 Antibody

Binding Specificity: N-Term

Purpose: EPHA3 Antibody - N-terminal region

Sequence: SVLDSFGELI PQPSNEVNLL DSKTIQGELG WISYPSHGWE EISGVDEHYT

Predicted Reactivity: Cow: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against EPHA3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human EPHA3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58618-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for EPH Receptor A3

Target: EPH Receptor A3 (EPHA3)

Alternative Name: EPHA3

Background:

Background Information: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.

Gene Name: EPH receptor A3

Alternative Symbols: EK4, ETK, HEK, ETK1, HEK4, TYRO4

Protein Name: Ephrin type-A receptor 3

Molecular Weight: 59kDa

Gene ID: 2042

NCBI Accession: NP_872585

UniProt: P29320

Pathways: RTK Signaling, Regulation of Cell Size