EIF2C3 antibody (N-Term)

Catalog No. ABIN786011

The Rabbit Polyclonal anti-EIF2C3 antibody is suitable to detect EIF2C3 in samples from Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Horse, Pig, Rabbit and Guinea Pig. It has been validated for WB.

Quick Overview for EIF2C3 antibody (N-Term) (ABIN786011)

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2C3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EIF2C3 Antibody

Binding Specificity: N-Term

Sequence: VHAVDVVLRH LPSMKYTPVG RSFFSAPEGY DHPLGGGREV WFGFHQSVRP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Eif2c3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 860 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EIF2C3

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Alternative Name: Eif2c3

Background: Eif2c3 is required for RNA-mediated gene silencing (RNAi). It binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. It lacks endonuclease activity and does not appear to cleave target mRNAs.
Alias Symbols: AW048688, Ago3, C130014L07Rik, Eif2c3
Protein Size: 860

Molecular Weight: 97 kDa

Gene ID: 214150

NCBI Accession: NM_153402, NP_700451

UniProt: Q8CJF9

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway