ATG4D antibody (Middle Region)

Catalog No. ABIN2787856

The Rabbit Polyclonal anti-ATG4D antibody is suitable to detect ATG4D in samples from Human, Mouse, Cow, Pig, Rabbit, Dog and Guinea Pig. It has been validated for WB.

Quick Overview for ATG4D antibody (Middle Region) (ABIN2787856)

Target: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Reactivity: Human, Mouse, Cow, Pig, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG4D antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATG4D Antibody

Binding Specificity: Middle Region

Purpose: ATG4D Antibody - middle region

Sequence: AQGAPELEQE RRHRQIVSWF ADHPRAPFGL HRLVELGQSS GKKAGDWYGP

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 90%, Pig: 100%, Rabbit: 100%

Characteristics: This is a rabbit polyclonal antibody against ATG4D. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATG4D

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58865-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATG4D

Target: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Alternative Name: ATG4D

Background:

Background Information: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.

Gene Name: ATG4 autophagy related 4 homolog D (S. cerevisiae)

Alternative Symbols: APG4D, AUTL4, APG4-D

Protein Name: Cysteine protease ATG4D

Molecular Weight: 53kDa

Gene ID: 84971

NCBI Accession: NP_116274

UniProt: Q86TL0

Pathways: Autophagy