UCHL1 antibody (C-Term)

Catalog No. ABIN2787897

This Rabbit Polyclonal antibody specifically detects UCHL1 in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio) and Horse.

Quick Overview for UCHL1 antibody (C-Term) (ABIN2787897)

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio), Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UCHL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-UCHL1 Antibody

Binding Specificity: C-Term

Sequence: HLYELDGRMP FPVNHGASSE DTLLKDAAKV CREFTEREQG EVRFSAVALC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against UCHL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human UCHL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 223 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UCHL1

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Alternative Name: UCHL1

Background: The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.
Alias Symbols: PARK5, PGP9.5, PGP95, Uch-L1, PGP 9.5
Protein Interaction Partner: UBC, ERN1, TNFRSF1A, NMRAL1, TRAF6, TRAF3, PMAIP1, CDK6, CDK5, CDK4, CDK1, IQCB1, RPTOR, DDB1, WDR82, TRIM63, USP28, TRIM54, USP21, USP15, NCAM1, AKT1, CDK2, ADRB2, ADRA2C, ADRA2B, ADRA2A, TERF2IP, TINF2, TUBA1A, LAMP2, HSP90AA1, HSPA8, PLA2G2A, CDKN2A, T
Protein Size: 223

Molecular Weight: 25 kDa

Gene ID: 7345

NCBI Accession: NM_004181, NP_004172

UniProt: P09936

Pathways: Feeding Behaviour