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LAG3 antibody (C-Term)

LAG3 Reactivity: Human, Mouse, Rat, Saccharomyces cerevisiae, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787950
  • Target See all LAG3 Antibodies
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Binding Specificity
    • 15
    • 14
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 87
    • 33
    • 9
    • 5
    • 4
    • 2
    • 1
    Human, Mouse, Rat, Saccharomyces cerevisiae, Rabbit
    Host
    • 51
    • 35
    • 7
    • 4
    Rabbit
    Clonality
    • 52
    • 42
    • 1
    Polyclonal
    Conjugate
    • 51
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LAG3 antibody is un-conjugated
    Application
    • 68
    • 36
    • 30
    • 29
    • 25
    • 22
    • 15
    • 13
    • 13
    • 10
    • 10
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    GFHLWRRQWR PRRFSALEQG IHPPQAQSKI EELEQEPEPE PEPEPEPEPE
    Predicted Reactivity
    Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Yeast: 100%
    Characteristics
    This is a rabbit polyclonal antibody against LAG3. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human LAG3
    Top Product
    Discover our top product LAG3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 525 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Alternative Name
    LAG3 (LAG3 Products)
    Synonyms
    CD223 antibody, LAG-3 antibody, Ly66 antibody, lymphocyte activating 3 antibody, lymphocyte-activation gene 3 antibody, LAG3 antibody, Lag3 antibody
    Background
    Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
    Alias Symbols: CD223
    Protein Interaction Partner: CENPJ, CEBPZ,
    Protein Size: 525
    Molecular Weight
    55 kDa
    Gene ID
    3902
    NCBI Accession
    NM_002286, NP_002277
    UniProt
    P18627
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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