TIMP3 antibody (N-Term)

Catalog No. ABIN2787970

Product Details anti-TIMP3 Antibody

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Sheep, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMP3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MTPWLGLIVL LGSWSLGDWG AEACTCSPSH PQDAFCNSDI VIRAKVVGKK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against TIMP3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TIMP3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 211 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TIMP3

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Alternative Name: TIMP3 (TIMP3 Products)

Synonyms: TIMP-3 antibody, TIMP3 antibody, timp3 antibody, HSMRK222 antibody, K222 antibody, K222TA2 antibody, SFD antibody, IMP-3 antibody, timp3-A antibody, Timp-3 antibody, metalloproteinase inhibitor 3 antibody, TIMP metallopeptidase inhibitor 3 antibody, Metalloproteinase inhibitor 3 antibody, TIMP metallopeptidase inhibitor 3 L homeolog antibody, tissue inhibitor of metalloproteinase 3 antibody, CpipJ_CPIJ003282 antibody, TIMP3 antibody, timp3 antibody, Timp3 antibody, timp3.L antibody

Background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
Alias Symbols: HSMRK222, K222, K222TA2, SFD
Protein Interaction Partner: AGTR2, ADAM17, EFEMP1, MMP14, MMP13, KDR, MMP3, MMP9, MMP2,
Protein Size: 211

Molecular Weight: 22 kDa

Gene ID: 7078

NCBI Accession: NM_000362, NP_000353

UniProt: P35625