FBXL12 antibody (C-Term)
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- Target See all FBXL12 Antibodies
- FBXL12 (F-Box and Leucine-Rich Repeat Protein 12 (FBXL12))
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Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Rat, Dog, Pig, Horse, Guinea Pig, Rabbit, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FBXL12 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PTEILSSCLT MPKLRVLELQ GLGWEGQEAE KILCKGLPHC MVIVRACPKE
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against FBXL12. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human FBXL12
- Top Product
- Discover our top product FBXL12 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 326 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FBXL12 (F-Box and Leucine-Rich Repeat Protein 12 (FBXL12))
- Alternative Name
- FBXL12 (FBXL12 Products)
- Synonyms
- Fbl12 antibody, FBXL12 antibody, fbl12 antibody, 3110048D16Rik antibody, F-box and leucine rich repeat protein 12 antibody, F-box and leucine-rich repeat protein 12 antibody, RNI-like superfamily protein antibody, FBXL12 antibody, Fbxl12 antibody, fbxl12 antibody, AT3G07550 antibody
- Background
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Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Alias Symbols: FLJ20188, Fbl12
Protein Interaction Partner: LNX1, DOCK8, PRAME, STYX, HSP90AA1, CUL1, SKP1, RNF32, ECSIT, MAST1, CDC37, PSEN2, PSEN1, APOE, A2M, UBC, COPS6, RBX1, CDKN1C, JUN, FXYD3, SMAD1, TGFBR1,
Protein Size: 326 - Molecular Weight
- 37 kDa
- Gene ID
- 54850
- NCBI Accession
- NM_017703, NP_060173
- UniProt
- Q9NXK8
- Pathways
- SARS-CoV-2 Protein Interactome
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