PEN2 antibody (N-Term)
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- Target See all PEN2 (PSENEN) Antibodies
- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Horse, Guinea Pig, Rabbit, Cow, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PEN2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LGGFAFLPFL WLVNIFWFFR EAFLAPAYTE QSQIKGYVWR SAVGFLFWVI
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against Psenen. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product PSENEN Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 101 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
- Alternative Name
- Psenen (PSENEN Products)
- Synonyms
- MSTP064 antibody, PEN-2 antibody, PEN2 antibody, Psenen antibody, ACYPI006208 antibody, 1700023M09Rik antibody, Pen-2 antibody, RGD1312037 antibody, CG33198 antibody, Dmel\\CG33198 antibody, anon-AE003800.1 antibody, dPen-2 antibody, psenen antibody, pen-2 antibody, pen2 antibody, zgc:109727 antibody, presenilin enhancer gamma-secretase subunit antibody, presenilin enhancer 2 antibody, presenilin enhancer gamma secretase subunit antibody, Gamma-secretase subunit pen-2 antibody, presenilin enhancer antibody, presenilin enhancer gamma secretase subunit S homeolog antibody, PSENEN antibody, PEN2 antibody, Psenen antibody, pen-2 antibody, psenen.S antibody, psenen antibody
- Background
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Psenen is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
Alias Symbols: 1700023M09Rik, MGC102026
Protein Interaction Partner: Psen2, Psen1,
Protein Size: 101 - Molecular Weight
- 12 kDa
- Gene ID
- 66340
- NCBI Accession
- NM_025498, NP_079774
- UniProt
- Q9CQR7
- Pathways
- Notch Signaling, Neurotrophin Signaling Pathway
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