SYT12 antibody (N-Term)

Catalog No. ABIN2788090

This Rabbit Polyclonal antibody specifically detects SYT12 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Dog and Guinea Pig.

Quick Overview for SYT12 antibody (N-Term) (ABIN2788090)

Target: SYT12 (Synaptotagmin XII (SYT12))

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYT12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SYT12 Antibody

Binding Specificity: N-Term

Purpose: SYT12 Antibody - N-terminal region

Sequence: AEAREKRVPA WNAQRASTRG PPSRKGSLSI EDTFESISEL GPLELMGREL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against SYT12. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SYT12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59489-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SYT12

Target: SYT12 (Synaptotagmin XII (SYT12))

Alternative Name: SYT12

Background:

Background Information: This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.

Gene Name: Synaptotagmin XII

Alternative Symbols: SYT11, sytXII

Protein Name: Synaptotagmin-12

Molecular Weight: 46kDa

Gene ID: 91683

NCBI Accession: NP_808878

UniProt: Q8IV01