ALDH5A1 antibody (Middle Region)

Catalog No. ABIN2788128

This anti-ALDH5A1 antibody is a Rabbit Polyclonal antibody detecting ALDH5A1 in WB. Suitable for Human, Rat, Cow, Rabbit and Guinea Pig.

Quick Overview for ALDH5A1 antibody (Middle Region) (ABIN2788128)

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Reactivity: Human, Rat, Cow, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH5A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALDH5A1 Antibody

Binding Specificity: Middle Region

Sequence: AFFLEWFSEE ARRVYGDIIH TPAKDRRALV LKQPIGVAAV ITPWNFPSAM

Predicted Reactivity: Cow: 86%, Guinea Pig: 79%, Human: 100%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ALDH5A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ALDH5A1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 535 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALDH5A1

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Alternative Name: ALDH5A1

Background: This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: SSADH, SSDH
Protein Interaction Partner: MAGEA11, TOMM40, VDAC1, TIAL1, SSBP1, SOD2, EBNA-LP, ABAT,
Protein Size: 535

Molecular Weight: 57 kDa

Gene ID: 7915

NCBI Accession: NM_001080, NP_001071

UniProt: P51649

Pathways: Monocarboxylic Acid Catabolic Process