ALDH5A1 antibody (AA 400-500)

Catalog No. ABIN7265542

This Rabbit Polyclonal antibody specifically detects ALDH5A1 in WB. It exhibits reactivity toward Human.

Quick Overview for ALDH5A1 antibody (AA 400-500) (ABIN7265542)

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH5A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALDH5A1 Antibody

Binding Specificity: AA 400-500

Purpose: ALDH5A1 Rabbit pAb

Sequence: VSKGATVVTG GKRHQLGKNF FEPTLLCNVT QDMLCTHEET FGPLAPVIKF DTEEEAIAIA NAADVGLAGY FYSQDPAQIW RVAEQLEVGM VGVNEGLISS V

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human ALDH5A1 (NP_001071.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ALDH5A1

Target: ALDH5A1 (Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Alternative Name: ALDH5A1

Background: This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.,ALDH5A1,SSADH,SSDH,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,Lipid Metabolism,Neuroscience,ALDH5A1

Molecular Weight: 57kDa/58kDa

Gene ID: 7915

UniProt: P51649

Pathways: Monocarboxylic Acid Catabolic Process