Calcitonin Receptor antibody (C-Term)

Catalog No. ABIN2788145

Product Details anti-Calcitonin Receptor Antibody

Target: Calcitonin Receptor (CALCR)

Binding Specificity: C-Term

Reactivity: Human, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calcitonin Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NQRWGRRPSN RSARAAAAAA EAGDIPIYIC HQELRNEPAN NQGEESAEII

Predicted Reactivity: Cow: 77%, Dog: 79%, Guinea Pig: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CALCR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CALCR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 474 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Calcitonin Receptor

Target: Calcitonin Receptor (CALCR)

Alternative Name: CALCR (CALCR Products)

Background: This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.
Alias Symbols: CRT, CTR, CTR1, CT-R
Protein Interaction Partner: GPRASP2, GPRASP1, RAMP3, RAMP1, FLNA, MBL2, CALM1, TOPBP1, TSHR, APOB, THBS1, LRP1, CALCA,
Protein Size: 474

Molecular Weight: 52 kDa

Gene ID: 799

NCBI Accession: NM_001742, NP_001733

UniProt: P30988

Pathways: cAMP Metabolic Process