Calcitonin Receptor antibody (AA 31-120)

Catalog No. ABIN725330

There are 4+ publications for this product available. The Rabbit Polyclonal anti-Calcitonin Receptor antibody is suitable to detect Calcitonin Receptor in samples from Rat. It has been validated for IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for Calcitonin Receptor antibody (AA 31-120) (ABIN725330)

Target: Calcitonin Receptor (CALCR)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calcitonin Receptor antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Calcitonin Receptor Antibody

Binding Specificity: AA 31-120

Purpose: Calcitonin receptor Polyclonal Antibody

Cross-Reactivity: Rat

Predicted Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat Calcitonin receptor

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Calcitonin Receptor antibody (ABIN725330)

Tsukamoto, Menuki, Murai, Hatakeyama, Takada, Furukawa, Sakai: "Elcatonin prevents bone loss caused by skeletal unloading by inhibiting preosteoclast fusion through the unloading-induced high expression of calcitonin receptors in bone marrow cells." in: Bone, Vol. 85, pp. 70-80, (2016) (PubMed).

Su, Gu, Dong, Mei: "Ibuprofen rescues abnormalities in periodontal tissues in conditional presenilin 1 and presenilin 2 double knockout mice." in: International journal of molecular sciences, Vol. 14, Issue 9, pp. 18457-69, (2013) (PubMed).

Han, Ji, Wang, Yan, Wang, Luo, Mei, Su: "Abnormalities in periodontal and salivary tissues in conditional presenilin 1 and presenilin 2 double knockout mice." in: Molecular and cellular biochemistry, Vol. 347, Issue 1-2, pp. 13-20, (2011) (PubMed).

Target Details for Calcitonin Receptor

Target: Calcitonin Receptor (CALCR)

Alternative Name: Calcitonin receptor

Background:

Synonyms: Calcitonin receptor, CT-R, C1A/C1B, Calcr

Background: This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.

Gene ID: 116506

UniProt: P32214

Pathways: cAMP Metabolic Process