Calcitonin Receptor antibody (AA 465-494)
Quick Overview for Calcitonin Receptor antibody (AA 465-494) (ABIN651875)
Target
See all Calcitonin Receptor (CALCR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Binding Specificity
- AA 465-494
-
Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
Immunogen
- This CALCR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids of human CALCR.
-
Isotype
- IgG
-
-
-
-
Application Notes
- IF: 1:10~50. WB: 1:1000. FC: 1:10~50
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
Expiry Date
- 6 months
-
-
- Calcitonin Receptor (CALCR)
-
Alternative Name
- CALCR
-
Background
- CALCR is a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis.
-
Molecular Weight
- 55329
-
Gene ID
- 799
-
NCBI Accession
- NP_001158209, NP_001158210, NP_001733
-
UniProt
- P30988
-
Pathways
- cAMP Metabolic Process
Target
-