Calcitonin Receptor antibody (C-Term)

Catalog No. ABIN213557

Product Details anti-Calcitonin Receptor Antibody

Target: Calcitonin Receptor (CALCR)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calcitonin Receptor antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human Calcitonin Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Gibbon, Monkey (95%) Marmoset, Dog, Panda, Guinea pig (84%).

Purification: Immunoaffinity purified

Immunogen: Synthetic 19 amino acid peptide from C-terminal cytoplasmic domain of human Calcitonin Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla (100%), Gibbon, Monkey (95%), Marmoset, Dog, Panda, Guinea pig (84%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: ELISA, IHC, IHC-P (20 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 20 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Expiry Date: 12 months

References for anti-Calcitonin Receptor antibody (ABIN213557)

Tur, Etschmann, Benz, Leich, Waller, Schuh, Rosenwald, Ertl, Kienitz, Haaf, Bräuninger, Gattenlöhner: "The 140-kD isoform of CD56 (NCAM1) directs the molecular pathogenesis of ischemic cardiomyopathy." in: The American journal of pathology, Vol. 182, Issue 4, pp. 1205-18, (2013) (PubMed).

Target Details for Calcitonin Receptor

Target: Calcitonin Receptor (CALCR)

Alternative Name: CALCR / Calcitonin Receptor (CALCR Products)

Synonyms: CALCR antibody, si:ch211-77k19.2 antibody, calcr antibody, CRT antibody, CT-R antibody, CTR antibody, CTR1 antibody, Clr antibody, Ct-R antibody, calcitonin receptor antibody, CALCR antibody, calcr antibody, Calcr antibody

Background: Name/Gene ID: CALCR
Subfamily: Calcitonin
Family: GPCR

Synonyms: CALCR, Calcitonin receptor, CRT, CT-R, CTR, CT receptor

Gene ID: 799

Pathways: cAMP Metabolic Process