IQCB1 antibody (C-Term)

Catalog No. ABIN2788212

Product Details anti-IQCB1 Antibody

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQCB1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LQHYFMGRAL EERAQQHREA LIAQISTNVE QLMKAPSLKE AEGKEPELFL

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against IQCB1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IQCB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 465 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IQCB1

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Alternative Name: IQCB1 (IQCB1 Products)

Synonyms: piq antibody, nphp5 antibody, slsn5 antibody, MGC81507 antibody, IQCB1 antibody, zgc:101792 antibody, MGC146213 antibody, 6820449I09Rik antibody, AV128382 antibody, NPHP5 antibody, PIQ antibody, SLSN5 antibody, IQ motif containing B1 antibody, IQ motif containing B1 L homeolog antibody, IQ calmodulin-binding motif containing 1 antibody, Iqcb1 antibody, iqcb1.L antibody, IQCB1 antibody, iqcb1 antibody

Background: This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants.
Alias Symbols: NPHP5, PIQ, SLSN5
Protein Interaction Partner: TUBB, KRT87P, ATP6V1G2, PRKDC, IGHG1, UBE2V1, HDAC6, ITGA11, TWF2, XPOT, NUDT3, RAB35, CPLX1, CDIPT, TUBB4B, TUBB3, BPNT1, TUBA1B, CALCOCO2, SEC16A, IQCB1, SGPL1, PEA15, DYNLL1, GEMIN2, HIRIP3, TUBA1A, YWHAB, UCHL1, UBB, TUBB2A, TUBA4A, HSP90B1, TPI1, THB
Protein Size: 465

Molecular Weight: 51 kDa

Gene ID: 9657

NCBI Accession: NM_001023571, NP_001018865

UniProt: Q3KS09