IQCB1 antibody (C-Term)

Catalog No. ABIN2788212

The Rabbit Polyclonal anti-IQCB1 antibody (ABIN2788212) specifically detects IQCB1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Rabbit, Cow and Guinea Pig samples.

Quick Overview for IQCB1 antibody (C-Term) (ABIN2788212)

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQCB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IQCB1 Antibody

Binding Specificity: C-Term

Purpose: IQCB1 Antibody - C-terminal region

Sequence: LQHYFMGRAL EERAQQHREA LIAQISTNVE QLMKAPSLKE AEGKEPELFL

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against IQCB1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IQCB1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59790-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IQCB1

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Alternative Name: IQCB1

Background:

Background Information: This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants.

Gene Name: IQ motif containing B1

Alternative Symbols: PIQ, NPHP5, SLSN5

Protein Name: IQ calmodulin-binding motif-containing protein 1

Molecular Weight: 51kDa

Gene ID: 9657

NCBI Accession: NP_001018865

UniProt: Q3KS09