NYS48/HAUS8 antibody (N-Term)

Catalog No. ABIN2788253

The Rabbit Polyclonal anti-NYS48/HAUS8 antibody (ABIN2788253) specifically detects NYS48/HAUS8 in WB. The antibody is reactive with Human and Pig samples.

Quick Overview for NYS48/HAUS8 antibody (N-Term) (ABIN2788253)

Target: NYS48/HAUS8 (HAUS8) (HAUS Augmin-Like Complex, Subunit 8 (HAUS8))

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NYS48/HAUS8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NYS48/HAUS8 Antibody

Binding Specificity: N-Term

Purpose: HAUS8 Antibody - N-terminal region

Sequence: QTRGKMSEGG RKSSLLQKSK ADSSGVGKGD LQSTLLEGHG TAPPDLDLSA

Predicted Reactivity: Human: 100%, Pig: 75%

Characteristics: This is a rabbit polyclonal antibody against HAUS8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HAUS8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59892-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NYS48/HAUS8

Target: NYS48/HAUS8 (HAUS8) (HAUS Augmin-Like Complex, Subunit 8 (HAUS8))

Alternative Name: HAUS8

Background:

Targeted Subunit: 8

Background Information: HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220], Uehara et al., 2009 [PubMed 19369198]).

Gene Name: HAUS augmin-like complex, subunit 8

Alternative Symbols: DGT4, HICE1, NY-SAR-48

Protein Name: HAUS augmin-like complex subunit 8

Molecular Weight: 45kDa

Gene ID: 93323

NCBI Accession: NP_219485

UniProt: Q9BT25