Rho-related GTP-binding protein antibody (C-Term)

Catalog No. ABIN2788258

The Rabbit Polyclonal anti-Rho-related GTP-binding protein antibody (ABIN2788258) specifically detects Rho-related GTP-binding protein in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit and Sheep samples.

Quick Overview for Rho-related GTP-binding protein antibody (C-Term) (ABIN2788258)

Target: Rho-related GTP-binding protein (RhO (pan))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Rho-related GTP-binding protein antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Rho-related GTP-binding protein Antibody

Binding Specificity: C-Term

Purpose: RHO Antibody - C-terminal region

Sequence: AFFAKSAAIY NPVIYIMMNK QFRNCMLTTI CCGKNPLGDD EASATVSKTE

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against RHO. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RHO

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59909-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Rho-related GTP-binding protein

Target: Rho-related GTP-binding protein (RhO (pan))

Alternative Name: RHO

Background:

Background Information: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.

Gene Name: Rhodopsin

Alternative Symbols: RP4, OPN2, CSNBAD1

Protein Name: Rhodopsin

Molecular Weight: 39kDa

Gene ID: 6010

NCBI Accession: NP_000530

UniProt: P08100