Rho-related GTP-binding protein antibody (C-Term)

Catalog No. ABIN2788258

Product Details anti-Rho-related GTP-binding protein Antibody

Target: Rho-related GTP-binding protein (RhO (pan))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Rho-related GTP-binding protein antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AFFAKSAAIY NPVIYIMMNK QFRNCMLTTI CCGKNPLGDD EASATVSKTE

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against RHO. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RHO

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 348 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Rho-related GTP-binding protein

Target: Rho-related GTP-binding protein (RhO (pan))

Alternative Name: RHO (RhO (pan) Products)

Target Type: Chemical

Background: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
Alias Symbols: CSNBAD1, MGC138309, MGC138311, OPN2, RP4
Protein Interaction Partner: DERL1, EDEM1, VCP, UBC, HSPA4, DNAJB2, RHO, PPP2CA, GRK5, GRK6, ARR3, GNGT1, SAG, GRK1, PRKCA, ADRBK1,
Protein Size: 348

Molecular Weight: 39 kDa

Gene ID: 6010

NCBI Accession: NM_000539, NP_000530

UniProt: P08100