ADAM8 antibody (N-Term)

Catalog No. ABIN2788269

This Rabbit Polyclonal antibody specifically detects ADAM8 in WB. It exhibits reactivity toward Human, Mouse, Rat and Rabbit.

Quick Overview for ADAM8 antibody (N-Term) (ABIN2788269)

Target: ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

Reactivity: Human, Mouse, Rat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADAM8 Antibody

Binding Specificity: N-Term

Purpose: ADAM8 Antibody - N-terminal region

Sequence: LHLRKNRDLL GSGYTETYTA ANGSEVTEQP RGQDHCFYQG HVEGYPDSAA

Predicted Reactivity: Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against ADAM8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ADAM8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59943-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADAM8

Target: ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

Alternative Name: ADAM8

Background:

Background Information: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma.

Gene Name: ADAM metallopeptidase domain 8

Alternative Symbols: MS2, CD156, CD156a

Molecular Weight: 94kDa

Gene ID: 101

NCBI Accession: NP_001100

UniProt: P78325

Pathways: Activation of Innate immune Response, M Phase