ADRA1B antibody (C-Term)
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- Target See all ADRA1B Antibodies
- ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ADRA1B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- YRPWTRGGSL ERSQSRKDSL DDSGSCLSGS QRTLPSASPS PGYLGRGAPP
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against ADRA1B. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human ADRA1B
- Top Product
- Discover our top product ADRA1B Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 520 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))
- Alternative Name
- ADRA1B (ADRA1B Products)
- Synonyms
- LOC100136712 antibody, [a]1b antibody, ADRA1 antibody, ALPHA1BAR antibody, RDC5 antibody, alpha-1B adrenoceptor antibody, adrenoceptor alpha 1B antibody, adrenergic receptor, alpha 1b antibody, LOC100136712 antibody, ADRA1B antibody, Adra1b antibody
- Background
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Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Alias Symbols: ADRA1, ALPHA1BAR
Protein Interaction Partner: ALB, AP2M1, GNAQ, STAT1, SAG, PRKCA, NOS1, GNA11, EZR, ADRA1A, FLNC,
Protein Size: 520 - Molecular Weight
- 57 kDa
- Gene ID
- 147
- NCBI Accession
- NM_000679, NP_000670
- UniProt
- P35368
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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