AP1B1 antibody (C-Term)

Catalog No. ABIN2788289

The Rabbit Polyclonal anti-AP1B1 antibody has been validated for WB. It is suitable to detect AP1B1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for AP1B1 antibody (C-Term) (ABIN2788289)

Target: AP1B1 (Adaptor-Related Protein Complex 1, beta 1 Subunit (AP1B1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP1B1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AP1B1 Antibody

Binding Specificity: C-Term

Sequence: KLFLKKPTET QELVQQVLSL ATQDSDNPDL RDRGYIYWRL LSTDPVAAKE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against AP1B1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AP1B1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 949 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AP1B1

Target: AP1B1 (Adaptor-Related Protein Complex 1, beta 1 Subunit (AP1B1))

Alternative Name: AP1B1

Background: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.
Alias Symbols: ADTB1, AP105A, BAM22, CLAPB2
Protein Interaction Partner: UBC, EGFR, RPA3, RPA2, RPA1, TRMT61A, DIABLO, INTS9, TBC1D2, TRIP10, ABCE1, PPP6R3, NTRK2, AP1G1, VCP, BARD1, AP1M1, AP1S2, AP1S1, EPS15, AP2M1, EPN1, SNAP91, CLINT1, COPS5, CUL3, SHBG, CDK2, SIRT7, SNCA, ATF7IP, KIF13A, ATM, AP1M2, PIP5K1C, BUB1B, BUB1,
Protein Size: 949

Molecular Weight: 104 kDa

Gene ID: 162

NCBI Accession: NM_001127, NP_001118

UniProt: Q10567