AP1B1 antibody (C-Term)

Catalog No. ABIN2788289

The Rabbit Polyclonal anti-AP1B1 antibody is suitable to detect AP1B1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB and IP.

Quick Overview for AP1B1 antibody (C-Term) (ABIN2788289)

Target: AP1B1 (Adaptor-Related Protein Complex 1, beta 1 Subunit (AP1B1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP1B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-AP1B1 Antibody

Binding Specificity: C-Term

Purpose: AP1B1 Antibody - C-terminal region

Sequence: KLFLKKPTET QELVQQVLSL ATQDSDNPDL RDRGYIYWRL LSTDPVAAKE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against AP1B1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AP1B1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59977-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for AP1B1

Target: AP1B1 (Adaptor-Related Protein Complex 1, beta 1 Subunit (AP1B1))

Alternative Name: AP1B1

Background:

Targeted Subunit: beta-1

Background Information: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.

Gene Name: Adaptor-related protein complex 1, beta 1 subunit

Alternative Symbols: ADTB1, BAM22, KIDAR, AP105A, CLAPB2

Protein Name: AP-1 complex subunit beta-1

Molecular Weight: 104kDa

Gene ID: 162

NCBI Accession: NP_001118

UniProt: Q10567