Apelin Receptor antibody (N-Term)

Catalog No. ABIN2788292

The Rabbit Polyclonal anti-Apelin Receptor antibody (ABIN2788292) specifically detects Apelin Receptor in WB. The antibody is reactive with Human, Rat, Mouse, Horse, Rabbit, Dog and Guinea Pig samples.

Quick Overview for Apelin Receptor antibody (N-Term) (ABIN2788292)

Target: Apelin Receptor (APLNR)

Reactivity: Human, Rat, Mouse, Horse, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apelin Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Apelin Receptor Antibody

Binding Specificity: N-Term

Purpose: APLNR Antibody - N-terminal region

Sequence: NGLVLWTVFR SSREKRRSAD IFIASLAVAD LTFVVTLPLW ATYTYRDYDW

Predicted Reactivity: Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against APLNR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human APLNR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59985-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Apelin Receptor

Target: Apelin Receptor (APLNR)

Alternative Name: APLNR

Background:

Background Information: This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.

Gene Name: Apelin receptor

Alternative Symbols: APJ, APJR, HG11, AGTRL1

Protein Name: Apelin receptor

Molecular Weight: 43kDa

Gene ID: 187

NCBI Accession: NP_005152

UniProt: P35414