Cathepsin E antibody (C-Term)

Catalog No. ABIN2788343

This Rabbit Polyclonal antibody specifically detects Cathepsin E in WB. It exhibits reactivity toward Human, Horse, Dog and Rabbit.

Quick Overview for Cathepsin E antibody (C-Term) (ABIN2788343)

Target: Cathepsin E (CTSE)

Reactivity: Human, Horse, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin E antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cathepsin E Antibody

Binding Specificity: C-Term

Purpose: CTSE Antibody - C-terminal region

Sequence: GILGLGYPSL AVGGVTPVFD NMMAQNLVDL PMFSVYMSSN PEGGAGSELI

Predicted Reactivity: Dog: 86%, Horse: 93%, Human: 100%, Rabbit: 92%

Characteristics: This is a rabbit polyclonal antibody against CTSE. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60125-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cathepsin E

Target: Cathepsin E (CTSE)

Alternative Name: CTSE

Background:

Background Information: The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.

Gene Name: Cathepsin E

Alternative Symbols: CATE

Protein Name: Cathepsin E

Molecular Weight: 40kDa

Gene ID: 1510

NCBI Accession: NP_683865

UniProt: P14091