MAP4 antibody (N-Term)

Catalog No. ABIN2788397

The Rabbit Polyclonal anti-MAP4 antibody (ABIN2788397) specifically detects MAP4 in IHC and WB. The antibody is reactive with Human samples.

Quick Overview for MAP4 antibody (N-Term) (ABIN2788397)

Target: MAP4 (Microtubule-Associated Protein 4 (MAP4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-MAP4 Antibody

Binding Specificity: N-Term

Purpose: MAP4 Antibody - N-terminal region

Sequence: LKETERASPI KMDLAPSKDM GPPKENKKET ERASPIKMDL APSKDMGPPK

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MAP4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60314-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAP4

Target: MAP4 (Microtubule-Associated Protein 4 (MAP4))

Alternative Name: MAP4

Background:

Background Information: MAP4 is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression.

Gene Name: Microtubule-associated protein 4

Alternative Symbols: DKFZp779A1753, MGC8617

Protein Name: Microtubule-associated protein 4

Molecular Weight: 121kDa

Gene ID: 4134

NCBI Accession: NP_002366

UniProt: P27816

Pathways: p53 Signaling, Microtubule Dynamics