CYB5R3 antibody (C-Term)
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- Target See all CYB5R3 Antibodies
- CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))
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Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYB5R3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IRAIMKDPDD HTVCHLLFAN QTEKDILLRP ELEELRNKHS ARFKLWYTLD
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against CYB5R3. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CYB5R3
- Top Product
- Discover our top product CYB5R3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 301 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))
- Alternative Name
- CYB5R3 (CYB5R3 Products)
- Synonyms
- B5R antibody, DIA1 antibody, Dia1 antibody, Nadhcb5 antibody, RNNADHCB5 antibody, 0610016L08Rik antibody, 2500002N19Rik antibody, C85115 antibody, Dia-1 antibody, WU:AL591952.1-001 antibody, WU:AL591952.1-002 antibody, WU:AL591952.1-003 antibody, WU:Cyb5r3 antibody, fc32h03 antibody, zgc:77071 antibody, wu:fc32h03 antibody, dia1 antibody, CB5R antibody, DDBDRAFT_0218707 antibody, DDBDRAFT_0266821 antibody, DDB_0218707 antibody, DDB_0266821 antibody, cytochrome b5 reductase 3 antibody, cytochrome b5 reductase 3 L homeolog antibody, NADH-cytochrome b5 reductase antibody, CYB5R3 antibody, Cyb5r3 antibody, cyb5r3 antibody, cyb5r3.L antibody, CNM00240 antibody, Tb11.47.0018 antibody, cyb5r1 antibody
- Background
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This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.
Alias Symbols: B5R, DIA1
Protein Interaction Partner: SUMO2, PARK2, UBC, SLC1A5, SDHA, RPS7, HSPA1L, CDK2, SPP1, CYB5R3, CYB5A, HBG2, CYCS, ESR1,
Protein Size: 301 - Molecular Weight
- 34 kDa
- Gene ID
- 1727
- NCBI Accession
- NM_000398, NP_000389
- UniProt
- P00387
- Pathways
- SARS-CoV-2 Protein Interactome
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