Cathepsin S antibody (N-Term)

Catalog No. ABIN2788630

This Rabbit Polyclonal antibody specifically detects Cathepsin S in WB. It exhibits reactivity toward Human, Rat, Cow, Horse, Dog, Guinea Pig, Rabbit and Pig.

Quick Overview for Cathepsin S antibody (N-Term) (ABIN2788630)

Target: Cathepsin S (CTSS)

Reactivity: Human, Rat, Cow, Horse, Dog, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin S antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cathepsin S Antibody

Binding Specificity: N-Term

Purpose: CTSS Antibody - N-terminal region

Sequence: QLHKDPTLDH HWHLWKKTYG KQYKEKNEEA VRRLIWEKNL KFVMLHNLEH

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against CTSS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CTSS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60953-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cathepsin S

Target: Cathepsin S (CTSS)

Alternative Name: CTSS

Background:

Background Information: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: Cathepsin S

Alternative Symbols: MGC3886

Protein Name: Cathepsin S

Molecular Weight: 37kDa

Gene ID: 1520

NCBI Accession: NP_004070

UniProt: P25774

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades