HPGD antibody (N-Term)

Catalog No. ABIN2788653

The Rabbit Polyclonal anti-HPGD antibody (ABIN2788653) specifically detects HPGD in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for HPGD antibody (N-Term) (ABIN2788653)

Target: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPGD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HPGD Antibody

Binding Specificity: N-Term

Purpose: HPGD Antibody - N-terminal region

Sequence: DQQQLRDTFR KVVDHFGRLD ILVNNAGVNN EKNWEKTLQI NLVSVISGTY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against HPGD. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61011-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HPGD

Target: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Alternative Name: HPGD

Background:

Background Information: This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Hydroxyprostaglandin dehydrogenase 15-(NAD)

Alternative Symbols: PGDH, PGDH1, PHOAR1, 15-PGDH, SDR36C1

Protein Name: 15-hydroxyprostaglandin dehydrogenase [NAD(+)]

Molecular Weight: 29kDa

Gene ID: 3248

NCBI Accession: NP_000851

UniProt: P15428