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CHRM1 antibody (C-Term)

The Rabbit Polyclonal anti-CHRM1 antibody has been validated for WB. It is suitable to detect CHRM1 in samples from Rat, Human, Mouse, Dog, Guinea Pig, Cow, Horse and Rabbit.
Catalog No. ABIN2788654

Quick Overview for CHRM1 antibody (C-Term) (ABIN2788654)

Target

See all CHRM1 Antibodies
CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Reactivity

Rat, Human, Mouse, Dog, Guinea Pig, Cow, Horse, Rabbit

Host

  • 49
  • 1
Rabbit

Clonality

  • 50
Polyclonal

Conjugate

  • 23
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CHRM1 antibody is un-conjugated

Application

  • 40
  • 15
  • 10
  • 7
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 12
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequence

    VKRPTKKGRD RAGKGQKPRG KEQLAKRKTF SLVKEKKAAR TLSAILLAFI

    Predicted Reactivity

    Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

    Characteristics

    This is a rabbit polyclonal antibody against CHRM1. It was validated on Western Blot.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human CHRM1
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 460 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

    Alternative Name

    CHRM1

    Background

    The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
    Alias Symbols: HM1, M1, M1R, MGC30125
    Protein Interaction Partner: CDC14A, GPRASP2, GPRASP1, Dlg4, GNAI2,
    Protein Size: 460

    Molecular Weight

    51 kDa

    Gene ID

    1128

    NCBI Accession

    NM_000738, NP_000729

    UniProt

    P11229

    Pathways

    Synaptic Membrane
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