CHRM1 antibody (C-Term)
Quick Overview for CHRM1 antibody (C-Term) (ABIN2788654)
Target
See all CHRM1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- VKRPTKKGRD RAGKGQKPRG KEQLAKRKTF SLVKEKKAAR TLSAILLAFI
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Predicted Reactivity
- Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
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Characteristics
- This is a rabbit polyclonal antibody against CHRM1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CHRM1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 460 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))
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Alternative Name
- CHRM1
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Background
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The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
Alias Symbols: HM1, M1, M1R, MGC30125
Protein Interaction Partner: CDC14A, GPRASP2, GPRASP1, Dlg4, GNAI2,
Protein Size: 460 -
Molecular Weight
- 51 kDa
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Gene ID
- 1128
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NCBI Accession
- NM_000738, NP_000729
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UniProt
- P11229
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Pathways
- Synaptic Membrane
Target
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