CHRM1 antibody (C-Term)

Catalog No. ABIN2788654

The Rabbit Polyclonal anti-CHRM1 antibody is suitable to detect CHRM1 in samples from Rat, Human, Mouse, Dog, Guinea Pig, Cow, Horse and Rabbit. It has been validated for WB.

Quick Overview for CHRM1 antibody (C-Term) (ABIN2788654)

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Reactivity: Rat, Human, Mouse, Dog, Guinea Pig, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHRM1 Antibody

Binding Specificity: C-Term

Purpose: CHRM1 Antibody - C-terminal region

Sequence: VKRPTKKGRD RAGKGQKPRG KEQLAKRKTF SLVKEKKAAR TLSAILLAFI

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CHRM1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CHRM1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61013-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRM1

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Alternative Name: CHRM1

Background:

Background Information: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.

Alternative Symbols: M1, HM1, M1R

Protein Name: Muscarinic acetylcholine receptor M1

Molecular Weight: 51kDa

Gene ID: 1128

NCBI Accession: NP_000729

UniProt: P11229

Pathways: Synaptic Membrane